Argatroban as an anticoagulant for both hematologic and chemical tests
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چکیده
منابع مشابه
Hirudin as an anticoagulant for both haematology and chemistry tests
Hirudin, an extract from the leech, has powerful antithrombin activity affecting the blood coagulation pathway. We evaluated the usefulness of hirudin in anticoagulating specimens for routine laboratory tests. Results using blood anticoagulated with hirudin corresponded well with results with blood treated with ethylenediamine tetraacetic acid (EDTA) in the complete blood count (CBC), including...
متن کاملCardiopulmonary bypass using argatroban as an anticoagulant for a 6.0-kg pediatric patient.
A patient was born with transposition of the great arteries, double-outlet right ventricle, interrupted aortic arch, and a ventricular septal defect and underwent a Damus-Kaye-Stansel procedure with a modified Blalock-Taussig shunt at 14 days old. Three months later, this patient presented with hypoxia and bradycardia was found to have a thrombus present in the main pulmonary artery extending t...
متن کاملEffects of argatroban as an anticoagulant for haemodialysis in patients with antithrombin III deficiency.
BACKGROUND In congenital or acquired antithrombin III-deficient patients undergoing haemodialysis, coagulation or residual blood in the blood circuit and dialyser is commonly observed under anticoagulation with heparin. Argatroban, a synthetic thrombin antagonist, directly inhibits thrombin activity in a manner that is different from that of heparin, thereby displaying an anticoagulating effect...
متن کاملDevelopment of argatroban as an anticoagulant and antithrombin agent in Japan.
Argatroban is a synthetic direct thrombin inhibitor which has been used in Japan for three indications, namely, chronic arterial occlusion, acute cerebral thrombosis and hemodialysis in AT-deficient patients or in patients with decreased AT. In patients with chronic arterial occlusion, argatroban increased the skin temperature, reduced the size of skin ulcers, and decreased the thrombin-antithr...
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ژورنال
عنوان ژورنال: Journal of Clinical Laboratory Analysis
سال: 2000
ISSN: 0887-8013,1098-2825
DOI: 10.1002/1098-2825(2000)14:4<136::aid-jcla2>3.0.co;2-1